The second round of the Winston-Salem Open was completed as several seeds fell as well as the highly-anticipated clash between Frances Tiafoe and Andy Murray taking place under the lights with the 13th-seeded American prevailing.

Top seed Pablo Carreno Busta clinched his spot in the third round and was joined by third seed Dan Evans, fourth seed Marton Fucsovics, ninth seed Jan-Lennard Struff, 12th seed Benoit Paire and 15th seed Carlos Alcaraz.

Fifth seed Alexander Bublik, sixth seed Marin Cilic, tenth seed Federico Delbonis and 11th seed Albert Ramos-Vinolas were all eliminated as the tournament is down to its final 16.

Wednesday's action

Tiafoe needed an hour and 50 minutes in hot, humid conditions to defeat Murray 7-6 (4), 6-3. The American saved three set points trailing 5-4 as he eyes a return to the Top 50.

Next up for him will be Brazil's Thiago Monteiro, who got past lucky loser Eduardo Nava 7-5, 6-1. Nava took the place of second seed David Goffin, who withdrew due to a 

Carreno Busta began his campaign with a 6-3, 3-6, 6-3 victory over Soon-woo Kwon in an hour, 56 minutes. The Spaniard won 69 percent of his first serve points and will next face 16th seed Dominik Koepfer.

"It was a very close match", he said in his on-court interview. "He played really well in the second and third sets. It is really nice to be here again. I am happy as it is important for me to start my first match with a victory.

"I feel really comfortable here; it is a nice way to go to New York before the US Open. It is important for me to play as many matches as possible."

Koepfer was a 5-7, 6-4, 6-4 winner over Marco Cecchinato and countryman Struff cruised past Gianluca Mager 6-2, 6-2 and next faces Ivashka, who upset Cilic 4-6, 7-5, 6-4.

It was also a strong day for France as Paire beat Gilles Simon 6-3, 6-3 and Pierre-Hugues Herbert had no problems beating Federico Coria 6-4, 6-2. Next up for Paire is Emil Ruusuvuori, who stunned Bublik 6-2, 7-6 (5) while Herbert next takes on Marcos Giron, a 6-3, 6-4 winner over Delbonis.

"It is not easy to play against Simon", Paire said. "I am so happy to beat him today. I played a good match and built on the confidence of last week. I am really happy to be back. 

"I reached the final in 2019, so I will try to do the same. The conditions are very tough. It is very humid. I have been in America for one month though, so I am used to it."

Evans fought past Lucas Pouille 3-6, 6-4, 6-1 and now faces another Frenchman in 14th seed Richard Gasquet, who won on Tuesday. Alcaraz withstood ten aces from Alexei Popyrin to knock out the Aussie 6-7 (9), 1-6, 7-6 (1).

The 18-year old Spaniard will challenge Fucsovics in the third round as the Hungarian eased past lucky loser Yosuke Watanuki 7-5, 6-1. Finally, Max Purcell saw off countryman Jordan Thompson 7-5, 6-4 and Mikael Ymer blew away Ramos-Vinolas 6-3, 6-1. The Aussie and Swede will next face each other.

Doubles results

There were only two doubles matches on Tuesday as Ivan Dodig and Austin Krajicek advanced past the American duo of Nicholas Monroe and Jackson Withrow 7-6 (3), 6-4 to reach the quarterfinals.

Joining them in the final eight will be Marcelo Arevalo and Matwe Middlekoop, who edged Andreas Mies and Andrey Golubev 6-2, 5-7, 11-9.

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