Liverpool will be eager to bounce back from their midweek Champions League defeat to Inter Milan.
Despite the Reds' 1-0 defeat at Anfield on Wednesday, Jurgen Klopp's side have won their last seven topflight matches.
The Seagull's have lost their last four, and will face a tough test against the Reds. Although, Graham Potter's side are unbeaten in their last three matches against Klopp's men, having won one and drawn two.
A victory for the visitors would close the gap to Manchester City at the top of the table to three points, whereas a home win would move Graham Potter's side up three places into 10th.
Team news
Ex-Liverpool midfielder Adam Lallana is a welcome return for the hosts, as well as Yves Bissouma, who could both feature.
Enock Mwepu is also in contention to return, however defender Adam Webster is likely to miss the game due to a groin injury.
Klopp has confirmed that Roberto Firmino will be available for the Reds, after taking part in full training.
However, the German boss also spoke about some Covid-19 problems within the squad, but didn't identify any specific individuals.
Ones to watch
Brighton - Neil Maupay
Potter's side have found goals hard to come by of late, and have scored just once in their last five matches.
However, Maupay is the Seagulls' top scorer this campaign with eight Premier League goals, and remains the hosts main threat up top.
Liverpool - Luis Diaz
Diaz has made an excellent start to his Liverpool career, and will be looking to find the back of the net on Saturday.
The Colombian has already made 17 attempts on goal in just four league matches since his arrival in January, and will likely be recalled to the Reds' lineup after his cameo appearance off the bench in midweek.
Predicted line-ups
Brighton: Sanchez, Veltman, Dunk, Duffy, Lamptey, Lallana, Bissouma, Moder, Cucurella, Trossard, Maupay.
Liverpool: Alisson, Alexander-Arnold, Matip, Van Dijk, Robertson, Fabinho, Henderson, Keita, Salah, Diaz, Mane.
Form guide
Brighton have won just once on their last six in all competitions, after an unbeaten run of seven matches.
Liverpool have picked up maximum points in their last seven league matches, and haven't been defeated away from home in the topflight since last year.
Prediction
Despite the hosts positive record against Klopp's side, the have been shipping too many goals of late and looking timid in front of goal.
The Reds should have enough to take all three points back to Merseyside and keep the pressure on Man City at the top of the table.
Prediction - Brighton 0-3 Liverpool
How to watch
The match will be available to watch in the UK on BT Sport, with a KO time of 12.30PM. The match highlights will also be available Saturday night on Match Of The Day, on BBC One at 10.20PM.