Queens Park Rangers will play fellow play-off chasers in a must-win game for both sides on Tuesday evening.
The hosts currently sit in eighth, two points above the traveling side who are in ninth.
Both sides have a game in hand on sixth place Blackburn Rovers who are just one point ahead of Sheffield United but are three points ahead of the Hoops. Therefore, a win for either team would be extremely beneficial towards a promotion charge.
One of the main things letting Rangers down is their goal difference, if they are going to challenge the teams above, they will need to improve it.
The visitors have lost the last three outings with only two wins in the last 11. The Blades’ form is slightly better, picking up four victories out of the last 11 and after a 1-0 loss away to Stoke City at the weekend, they'll be looking to get back to winning ways.
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Team news
The home team have suffered a lot of injuries over the past few months and will still be without their top goalscorer Billy Sharp after he picked up a hamstring injury against Barnsley.
Paul Heckingbottom may also recall attacking midfielder Iliman Ndiaye back into the starting eleven.
Morgan Gibbs-White will be back to full fitness after picking up an illness just before the game against Stoke.
Star man Chris Willock is still out after suffering a hamstring injury and won't make a return for the remainder of the campaign.
Goalkeepers David Marshall and Seny Diang are still on the physio table, meaning Kieran Westwood remains between the sticks.
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Predicted lineups
Sheffield United (3-4-2-1)
Foderingham, Robinson, Egan, Davies, Norrington-Davies, Berge, Norwood, Baldock, Gibbs-White, Ndiaye, Jebbison.
Queens Park Rangers (3-4-2-1)
Westwood, Sanderson, Dunne, Dickie, Wallace, Johansen, Field, Odubajo, Dozzell, Chair, Dykes.
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Ones to watch
The 22-year-old has cemented his spot as one of the best players in the EFL since joining United on loan from Wolves in August.
He has racked up a total of nine goals and seven assists in 28 matches this season, scoring most recently in a 2-0 win over strugglers Barnsley.
Also a danger from attacking midfield, Chair has scored eight and assisted four this season.
Since coming back from a loan move to Stevenage, the 24-year-old has clearly impressed Mark Warburton and has become a regular starter for the R's.
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Previous meetings
The reverse fixture between the two sides was meant to take place on December 30 2021 but due to Covid 19 cases within QPR, it had to be postponed.
It is now set to take place at Loftus Road on April 30 2022.
The last time these two sides met was January 12 2019 where the blades defeated their opponents by one goal to nil thanks to a David McGoldrick strike.
The visitors haven't defeated the Sheffield side since the 31st October 2017 so will be looking to make a change.
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How to watch
The game kicks off at 19:45 BST on Tuesday April 5.
It is not available to watch in the UK but overseas supporters can purchase a live stream of the game via either club website.
Audio options are also available.