Stoke City's form has improved in recent weeks, with three wins in their last five games as they make a late surge to finish in the top half of the Championship table.
The Potters' last game was a comprehensive 3-1 away win against West Brom, with an own goal and strikes from Jacob Brown and Lewis Baker.
Michael O'Neill's side sit in 15th position in the standings, two points from the Albion in 12th.
Bristol City have endured a season of transition under Nigel Pearson after sitting in the bottom six of the table for the majority of the campaign, as they currently sit 19th.
The Robins have won just one of their last eight games, with two draws and five losses.
Their last game was a 1-1 draw to bottom of the table Peterborough United after a late Posh equaliser.
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Team news
Sam Clucas and Morgan Fox will not play a part after picking up quad and hamstring strains respectively in training.
Nick Powell remains sidelined with a quad injury, and looks unlikely to play a part before the end of the season.
Harry Souttar and Jordan Thompson will both return to action in pre-season after suffering long-term injuries.
Bristol City
George Tanner is back in training but will not make the trip to Staffordshire after recovering from a hamstring injury.
Callum O'Dowda and Andy King remain out, but are set to be fit to play next week.
Tomas Kalas is still facing time on the sidelines and is unlikely to feature again before the end of the campaign as he recovers from a groin injury.
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Predicted lineups
Stoke City (3-5-2)
Bonham; Forrester, Jagielka, Harwood-Bellis; Smith, Allen, Baker, Vrancic, Tymon; Brown, Maja.
Bristol City (3-4-1-2)
Bentley; Vyner, Klose, Atkinson; Scott, James, Massengo, Dasilva; Weimann; Wells, Martin.
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Ones to watch
Baker arrived in North Staffordshire in January, and his good form since joining has seen him win the club's Player of the Month award for February. He departed Chelsea in the window after being contracted with the club since 2014, making just two appearances in that time.
His most notable loan spells have been at Vitesse, Reading and Trabzonspor, where he picked up a Turkish Super Cup medal in 2020. The 26-year-old has scored eight goals and notched two assists in his first 16 league games for Stoke, despite being employed in a box-to-box midfield role.
Weimann has been the shining light in a tough season for Bristol City, and is enjoying his best season in a Robins shirt after joining from Derby County in 2018. Most known for his spell at Aston Villa in the Premier League, he has also played 16 times for his native Austria.
This season he has netted 19 times in 41 games, making him the league's fourth-highest scorer.
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Previous meetings
The reverse fixture saw Bristol City run out 1-0 victors with Tyreeq Bakinson netting the winner.
After losing just three of their first 23 home league games against Bristol City between 1906 and 2008, Stoke have lost the last three in a row.
The Robins are looking to record their first league double over the Potters since 1907.
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How to watch
The game kicks off at 15:00 BST on Friday April 15.
It is not available to watch in the UK but overseas supporters can purchase a live stream of the game via either club website.